KEZAVA EXTRACT 

Sepsis  

  

Every minute matters in sepsis. Not every hour. Not every shift. Every single minute from the moment a patient’s condition begins to turn. 

Yet across hospitals every day, the data systems meant to support sepsis care are working against the very teams trying to save lives. Quality nurses buried in spreadsheets. Compliance officers chasing timestamps across fragmented charts. Clinical leaders making decisions based on reports that are already three weeks old before they land in the meeting room. 

This is not a people problem. The teams managing sepsis programs are dedicated, skilled, and working as hard as they possibly can. This is a systems problem. And it is one that Kezava Extract is purpose built to solve. 

  

#1 

Sepsis is the leading cause of hospital deaths in the United States 

80% 

Of sepsis deaths are potentially preventable with timely intervention 

1 in 3 

Patients who die in a hospital has sepsis at the time of death 

  

What Is Actually Happening on the Ground 

Walk into most hospital quality departments today and you will find the same scene. A team of talented professionals doing important work in the least efficient way imaginable. 

Blood culture timestamps pulled manually from the lab system. Antibiotic administration times cross-referenced against nursing notes. Lactate results tracked down in a separate module. Fluid resuscitation documented in yet another section of the chart. All of it assembled by hand, case by case, into a spreadsheet that is already out of date by the time it is complete. 

This is how sepsis data management works in most hospitals right now. And it is costing more than anyone fully accounts for, in staff time, in compliance risk, in delayed quality improvement, and ultimately in patient outcomes that could have been better with faster, more reliable information. 

The Gaps That Put Patients at Risk 

Recognition Gap 

Sepsis rarely announces itself with clarity. Patients present with subtle, overlapping symptoms that can easily be attributed to other causes, especially in busy emergency departments and understaffed overnight units. Without a systematic, real-time approach to identifying at-risk patients, recognition happens too late for early intervention to change the trajectory of the case. 

Documentation Gap 

Sepsis care unfolds across multiple teams, multiple shifts, and multiple systems simultaneously. Capturing a complete and accurate record of everything that happened, when it happened, and who ordered it is extraordinarily difficult when the information is scattered across an EHR that was never designed to tell a cohesive clinical story. 

Compliance Gap 

CMS Sepsis Bundle requirements are precise and unforgiving. Every key intervention needs to be documented with accurate timestamps. When documentation is incomplete or inconsistently captured, hospitals face compliance exposure, reimbursement challenges, and public reporting outcomes that do not reflect the true quality of care being delivered. 

Coordination Gap 

No single team owns sepsis. Emergency physicians, hospitalists, intensivists, nurses, pharmacists, and laboratory staff all play a role. Without a system that connects these disciplines around a shared, real-time picture of each patient, coordination breaks down at exactly the moments when it needs to be strongest. 

Improvement Gap 

Quality improvement requires time and mental bandwidth. When the team responsible for improving sepsis outcomes is spending most of their working hours collecting and validating data, there is simply not enough of either left to do the work that actually changes things. The data gets gathered. The improvement never quite happens. 

How Kezava Extract Helps 

Identification 

Kezava Extract monitors clinical data across your EMR continuously, flagging patients who meet sepsis screening criteria in real time based on vital signs, lab values, and clinical documentation. Early identification creates the window for early intervention, which is where outcomes are actually decided. 

Abstraction 

The platform reads and interprets clinical documentation automatically, extracting every key data element needed for sepsis registry reporting. Antibiotic timing, culture collection, lactate trends, fluid administration, and clinical response are all captured accurately and consistently, without anyone having to open a chart manually. 

Bundle Compliance Tracking 

Abstracted data maps directly to CMS Sepsis Bundle requirements, giving quality teams a live view of compliance across every active and recently closed case. Gaps are visible the moment they appear, creating the opportunity to address documentation issues before they become audit findings. 

Workflow Management 

Every member of the quality team gets a clear, prioritized view of where cases stand. Outstanding documentation flags, compliance status indicators, and key case milestones are all visible in one place. Nothing gets overlooked. No case quietly falls through the cracks at month end. 

Live Reporting and Analytics 

Clinical leaders get dashboards that reflect what is happening right now, not what was happening three weeks ago. Bundle compliance rates, time to antibiotic, mortality trends, and length of stay data are available in real time, so decisions are made on current information rather than historical snapshots. 

Continuous Improvement 

When data is accurate, complete, and available in real time, quality improvement stops being reactive and starts being intentional. Teams can identify patterns in delayed recognition, trace compliance gaps to their root causes, and implement changes while the learning is still directly connected to the cases that generated it. 

What Changes When the System Works 

The impact of getting sepsis data management right reaches further than most organizations expect when they first begin to think about it. 

Clinical staff reclaim hours every week that were previously consumed by manual abstraction. Quality nurses shift from spending most of their time gathering data to spending it analysing data and leading improvement conversations that matter. Compliance positions strengthen because gaps are visible in real time rather than discovered during retrospective audits. And perhaps most importantly, care teams have the information they need to act faster and more consistently, which is where the difference between survival and mortality is often made. 

Sepsis will always demand the best from the people caring for patients at the bedside. The systems supporting that care should demand the same of themselves. 

Every minute matters in sepsis care. Not every hour. Not every shift. Every single minute from the moment a patient’s condition begins to deteriorate. 

Yet in many hospitals today, the systems meant to support sepsis management are slowing teams down instead of enabling them to act faster. 

Quality nurses manually reviewing charts. Compliance teams chasing timestamps across fragmented EMRs. Clinical leaders relying on reports that are already weeks old before meaningful action can be taken. 

This is not a people problem. The teams running sepsis programs are highly skilled and deeply committed. The challenge is that most hospitals are still relying on workflows that were never designed for real-time sepsis surveillance, abstraction, and quality improvement. 

That is exactly where Kezava Extract fits in. 

#1 Cause of Hospital Deaths in the U.S. 

80% of sepsis deaths are considered potentially preventable with timely recognition and intervention. 

1 in 3 patients who die in hospitals has sepsis at the time of death. 

The Operational Reality Behind Sepsis Programs 

Across hospitals, sepsis management often depends on manual effort spread across disconnected systems. 

Blood culture collection times are retrieved from a single module. Antibiotic administration times are validated against nursing documentation. Lactate trends are reviewed separately. Fluid resuscitation documentation sits elsewhere in the chart. 

Teams then spend hours consolidating this information manually for CMS SEP-1 reporting, internal audits, registry abstraction, and quality reviews. 

By the time the data is assembled, the opportunity for proactive intervention or operational improvement has often already passed. 

Kezava Extract was designed specifically to eliminate this operational burden. 

The Key Gaps Hospitals Face in Sepsis Management 

Recognition Gap 

Sepsis rarely presents straightforwardly. Early indicators are often subtle and distributed across vitals, labs, physician notes, nursing assessments, and medication orders. 

Kezava Extract continuously monitors structured and unstructured clinical data within the EMR to help identify patients who meet sepsis screening criteria earlier, creating an opportunity for faster intervention. 

Documentation Gap 

Sepsis care spans multiple departments, providers, and shifts. Capturing an accurate timeline manually is difficult, especially when critical data points are scattered throughout the EMR. 

Kezava Extract automatically abstracts key clinical and operational data elements directly from the chart, including: 

  • Antibiotic administration timing
    • Blood culture collection
    • Lactate measurements and trends
    • Fluid resuscitation documentation
    • Provider documentation and clinical indicators
    • Response timelines and escalation events 

This creates a complete, consistent clinical story without requiring manual chart review. 

Compliance Gap 

CMS SEP-1 compliance requirements are highly detailed and timestamp-dependent. Even when care delivery is appropriate, incomplete or inconsistent documentation can negatively impact reporting and reimbursement. 

Kezava Extract maps abstracted data directly to SEP-1 and hospital-defined quality measures, giving teams real-time visibility into compliance performance and documentation gaps before retrospective audits uncover them. 

Coordination Gap 

Sepsis care involves emergency physicians, intensivists, nurses, pharmacists, laboratory teams, and quality departments simultaneously. 

Kezava Extract centralizes relevant clinical and workflow information into a unified operational view, helping teams stay aligned around patient status, bundle completion, outstanding tasks, and documentation requirements. 

Improvement Gap 

Most quality teams spend the majority of their time gathering and validating data rather than driving improvement initiatives. 

By automating abstraction and reporting workflows, Kezava Extract allows quality and clinical leadership teams to focus on: 

  • Root cause analysis
    • Care pathway optimization
    • Recognition pattern analysis
    • Process improvement initiatives
    • Outcome tracking and performance benchmarking 

How Kezava Extract Supports Sepsis Programs 

Real-Time Clinical Surveillance 

Continuous monitoring of EMR data to identify patients at risk for sepsis based on clinical criteria, vitals, labs, and documentation patterns. 

Automated Data Abstraction 

AI-driven extraction of structured and unstructured clinical data is required for SEP-1 reporting, registries, quality initiatives, and operational reviews. 

Live Compliance Tracking 

Real-time monitoring of bundle adherence, documentation completeness, and critical intervention timelines. 

Workflow Visibility 

Centralized dashboards that allow quality teams to prioritize cases, identify missing documentation, and manage abstraction workflows efficiently. 

Operational Analytics 

Live reporting on: 

  • Time to antibiotics
    • Bundle compliance performance
    • Mortality trends
    • ICU utilization
    • Length of stay
    • Readmission patterns
    • Documentation variance trends 

Continuous Quality Improvement 

With accurate, real-time data available continuously, hospitals can move from retrospective reporting to proactive quality management. 

What Changes When the System Works 

When sepsis data workflows become automated and actionable: 

  • Quality nurses spend less time manually abstracting charts
    • Compliance teams gain earlier visibility into gaps
    • Clinical leaders receive real-time operational intelligence
    • Care teams can intervene faster and more consistently
    • Hospitals strengthen quality reporting and reimbursement performance
    • Improvement initiatives become data-driven instead of reactive 

Most importantly, hospitals create an environment where clinicians can focus more of their time on patient care instead of administrative data collection. 

Sepsis will always require rapid clinical judgment and coordinated care delivery. 

The systems supporting those teams should operate with the same urgency.